Mes1 controls the meiosis I to meiosis II transition by distinctly regulating the anaphase-promoting complex/cyclosome coactivators Fzr1/Mfr1 and Slp1 in fission yeast

摘要

Although meiosis is extremely important not only for sexual reproduction but also for creating diversity, very little is known about meiotic regulation. Five APC/C coactivators have been found in the fission yeast genome. This study investigates how all the coactivators are involved in the meiosis I/meiosis II transition.